This product was a last resort for me prior to seeing a doctor, who most likely would have prescribed antibiotics. I had been dealing with bacterial vaginosis for several weeks and had tried hydrogen peroxide douches (which evidently has worked for many women) as well as another product, femdophilus. Nothing had worked for me yet. And at first, I did not think this product was working either. It is supposed to be taken regularly for 14 days, and the two weeks was almost up before my symptoms ceased. But the symptoms did go away by the time the 14 days was finished. That was about two months ago, and the infection has not returned.I was hesitant about the effectiveness of the product simply because I ordered it. I've read on the web that the heat a product like this might be exposed to during shipping might damage its effectiveness (and I placed this order in August!). But the product worked nevertheless.I have suffered from burning and itching before my period forever. Cultures for yeast always negative so my doctor suggested something homeopathic. This product works great ! I use it for several days in a row before and after my period. I insert the capsules with an applicator from some OTC vaginal yeast ointment.I don't use the oral pill so I only gave it 4 stars since I don't need it. I take a much stronger oral probiotic called Raw Probiotics Vaginal Care. Wish they just sold a larger quantity of the vaginal capsules.I was drawn to trying the product because of the many articles and even my own OBGYN saying that boric acid was promoted by a fair number of doctors and had high success rates. And there were some very promising customer reviews of this product. So I'm not disputing any of that . However, my personal experience was a bad reaction, far worsening symptoms and some new ones. I went back to my doctor and then decided to try traditional Chinese and Hawaiian medicine which worked better for me. If you know the product works for you, that's great. Just be advised that not everybody does. Not sure if lack of refrigeration in transit affected anything but the product is supposed to stay cold and it was not. The original company keeps it cold and I did also order from them but am unwilling to try it now.They changed the formula to this product, the suppositories used to pink now the're yellow and they irritate but my issue resolved after awhile...It helped a little, but it really burned, especially at first. I prefer pure boric acid.I've used this for years and always works as intended. My flora was imbalanced and GY-Na-Tren restores it.This need to be cold delivered cold says the manufacturer.Excellent product for candida...The only one that really works! & cost is quite reasonable.