Uses: Selenium is a factor in the maintenance of healthy body cells and tissues and is also used for any number of conditions that are caused or exacerbated by oxidative stress. Adverse Side Effects: Selenium toxicity should not be expected in daily amountsup to 200mcg. American public health surveys carried out in seleniferous areas of the United States failed to establish any symptoms specific to selenium poisoning. Even with an average daily intake of 724 mcg amount North Dakota and Wyoming ranchers living in seleniferous areas, signs of symptoms of selenium overexposure were not observed. However, these kinds of high numbers should not be sought by those supplementing with selenium, as indicated in the next paragraph. Selenium toxicity results in loss of hair and nails, lesions of the skin, nervous system, and possible teeth. Reported intake thresholds for these kinds of toxicity have included 750 mcg and 910 mcg. Interations: Selenium and vitamin E work together to enhance the protection of cellular membranes from peroxidation. This is though to extend from increased glutathione redox activity on vitamin E. Similarly, glutathione is able to reduce oxidized vitamin C, which is then able to reduce membrane Vitamin E. Unlike many mineral absorption patterns, selenium is relatively easy to absorb, and the more so when presented in organic forms, as is commonly the case in commercial supplements. The mechanism of absorption is not regulated by a homeostasis control, thus making selenium toxicity possible in the uninitiated, with up to 50 to 100 percent absorption regardless of the persons existing selenium status. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.